S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury

Neuroinflammation following traumatic brain injury (TBI) is increasingly recognized to contribute to chronic tissue loss and neurologic dysfunction. Circulating levels of S100B increase after TBI and have been used as a biomarker. S100B is produced by activated astrocytes and can promote microglial...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Kabadi, Shruti V, Stoica, Bogdan A, Zimmer, Danna B, Afanador, Lauriaselle, Duffy, Kara B, Loane, David J, Faden, Alan I
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671122/
https://ncbi.nlm.nih.gov/pubmed/26154869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.165
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