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Identification of the HIV-1 Vif and human APOBEC3G protein interface
Human cells express natural antiviral proteins, such as APOBEC3G (A3G) that potently restrict HIV replication. As a counter defense, HIV encodes the accessory protein Vif, which binds A3G and mediates its proteasomal degradation. Our structural knowledge on how Vif and A3G interact is very limited s...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670588/ https://ncbi.nlm.nih.gov/pubmed/26628364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.068 |
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