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The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is characterized by senile plaques, extracellular deposits composed primarily of amyloid–beta (Aβ), and neurofibrillary tangles, which are abnormal intracellular inclusions containing hyperphosphorylated tau. The amyloid cascade hypothesis posits that the deposit...
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| 出版年: | Mol Brain |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670528/ https://ncbi.nlm.nih.gov/pubmed/26637371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0174-2 |
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