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The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by senile plaques, extracellular deposits composed primarily of amyloid–beta (Aβ), and neurofibrillary tangles, which are abnormal intracellular inclusions containing hyperphosphorylated tau. The amyloid cascade hypothesis posits that the deposit...

詳細記述

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書誌詳細
出版年:Mol Brain
主要な著者: Watanabe, Kiwamu, Uemura, Kengo, Asada, Megumi, Maesako, Masato, Akiyama, Haruhiko, Shimohama, Shun, Takahashi, Ryosuke, Kinoshita, Ayae
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670528/
https://ncbi.nlm.nih.gov/pubmed/26637371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0174-2
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