The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by senile plaques, extracellular deposits composed primarily of amyloid–beta (Aβ), and neurofibrillary tangles, which are abnormal intracellular inclusions containing hyperphosphorylated tau. The amyloid cascade hypothesis posits that the deposit...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Brain
Auteurs principaux: Watanabe, Kiwamu, Uemura, Kengo, Asada, Megumi, Maesako, Masato, Akiyama, Haruhiko, Shimohama, Shun, Takahashi, Ryosuke, Kinoshita, Ayae
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670528/
https://ncbi.nlm.nih.gov/pubmed/26637371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0174-2
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