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The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is characterized by senile plaques, extracellular deposits composed primarily of amyloid–beta (Aβ), and neurofibrillary tangles, which are abnormal intracellular inclusions containing hyperphosphorylated tau. The amyloid cascade hypothesis posits that the deposit...
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| Pubblicato in: | Mol Brain |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670528/ https://ncbi.nlm.nih.gov/pubmed/26637371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0174-2 |
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