The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is characterized by senile plaques, extracellular deposits composed primarily of amyloid–beta (Aβ), and neurofibrillary tangles, which are abnormal intracellular inclusions containing hyperphosphorylated tau. The amyloid cascade hypothesis posits that the deposit...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Watanabe, Kiwamu, Uemura, Kengo, Asada, Megumi, Maesako, Masato, Akiyama, Haruhiko, Shimohama, Shun, Takahashi, Ryosuke, Kinoshita, Ayae
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670528/
https://ncbi.nlm.nih.gov/pubmed/26637371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0174-2
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