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The BH3-only protein Bad is dispensable for TNF-mediated cell death

Tumor necrosis factor (TNF) is a key signaling molecule orchestrating immune and inflammatory responses and possesses the capacity to trigger apoptotic as well as necroptotic cell death. Apoptotic cell death elicited by TNF has been demonstrated to engage pro-apoptotic Bcl-2 family proteins, most pr...

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Pubblicato in:Cell Death Dis
Autori principali: Ottina, E, Sochalska, M, Sgonc, R, Villunger, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669773/
https://ncbi.nlm.nih.gov/pubmed/25611386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.575
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