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The BH3-only protein Bad is dispensable for TNF-mediated cell death

Tumor necrosis factor (TNF) is a key signaling molecule orchestrating immune and inflammatory responses and possesses the capacity to trigger apoptotic as well as necroptotic cell death. Apoptotic cell death elicited by TNF has been demonstrated to engage pro-apoptotic Bcl-2 family proteins, most pr...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Ottina, E, Sochalska, M, Sgonc, R, Villunger, A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669773/
https://ncbi.nlm.nih.gov/pubmed/25611386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.575
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