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Pharmacologic inhibition of lactate production prevents myofibroblast differentiation
Myofibroblasts are one of the primary cell types responsible for the accumulation of extracellular matrix in fibrosing diseases, and targeting myofibroblast differentiation is an important therapeutic strategy for the treatment of pulmonary fibrosis. Transforming growth factor-β (TGF-β) has been sho...
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出版年: | Am J Physiol Lung Cell Mol Physiol |
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主要な著者: | , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
American Physiological Society
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4669339/ https://ncbi.nlm.nih.gov/pubmed/26408551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00058.2015 |
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