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Pharmacologic inhibition of lactate production prevents myofibroblast differentiation

Myofibroblasts are one of the primary cell types responsible for the accumulation of extracellular matrix in fibrosing diseases, and targeting myofibroblast differentiation is an important therapeutic strategy for the treatment of pulmonary fibrosis. Transforming growth factor-β (TGF-β) has been sho...

詳細記述

保存先:
書誌詳細
出版年:Am J Physiol Lung Cell Mol Physiol
主要な著者: Kottmann, Robert Matthew, Trawick, Emma, Judge, Jennifer L., Wahl, Lindsay A., Epa, Amali P., Owens, Kristina M., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669339/
https://ncbi.nlm.nih.gov/pubmed/26408551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00058.2015
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