Activated human T lymphocytes inhibit TGFβ-induced fibroblast to myofibroblast differentiation via prostaglandins D(2) and E(2)

In pulmonary fibrosis (PF), fibroblasts and myofibroblasts proliferate and deposit excessive extracellular matrix in the interstitium, impairing normal lung function. Because most forms of PF have a poor prognosis and limited treatment options, PF represents an urgent unmet need for novel, effective...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Lacy, Shannon H., Epa, Amali P., Pollock, Stephen J., Woeller, Collynn F., Thatcher, Thomas H., Phipps, Richard P., Sime, Patricia J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966783/
https://ncbi.nlm.nih.gov/pubmed/29351444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00565.2016
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