Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol

Pulmonary fibrosis is a chronic and irreversible scarring disease in the lung with poor prognosis. Few therapies are available; therefore it is critical to identify new therapeutic targets. Our lab has previously identified the enzyme lactate dehydrogenase-A (LDHA) as a potential therapeutic target...

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Publicado en:PLoS One
Autores principales: Judge, Jennifer L., Nagel, David J., Owens, Kristina M., Rackow, Ashley, Phipps, Richard P., Sime, Patricia J., Kottmann, R. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967738/
https://ncbi.nlm.nih.gov/pubmed/29795645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197936
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