Influence of Molecular Weight of Carriers and Processing Parameters on the Extrudability, Drug Release, and Stability of Fenofibrate Formulations Processed by Hot-Melt Extrusion

The objective of this study was to investigate the extrudability, drug release, and stability of fenofibrate (FF) formulations utilizing various hot-melt extrusion processing parameters and polyvinylpyrrolidone (PVP) polymers of various molecular weights. The different PVP grades selected for this s...

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Detalhes bibliográficos
Publicado no:J Drug Deliv Sci Technol
Main Authors: Alsulays, Bader B., Park, Jun-Bom, Alshehri, Sultan M., Morott, Joseph T., Alshahrani, Saad M., Tiwari, Roshan V., Alshetaili, Abdullah S., Majumdar, Soumyajit, Langley, Nigel, Kolter, Karl, Gryczke, Andreas, Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668592/
https://ncbi.nlm.nih.gov/pubmed/26640526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2015.07.011
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