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Hot melt extrusion as an approach to improve solubility, permeability and oral absorption of a psychoactive natural product, piperine
OBJECTIVE: The aims of the current research project were to investigate the efficiency of various polymers to enhance the solubility and increase the systemic absorption of piperine using hot melt extrusion technology. METHODS: Piperine 10–40% w/w and Eudragit® EPO/Kollidon® VA 64 or Soluplus® were...
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| Publicado no: | J Pharm Pharmacol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931965/ https://ncbi.nlm.nih.gov/pubmed/27283755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jphp.12579 |
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