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Influence of Degassing on Hot-Melt Extrusion Process

The present study aimed to evaluate the effect of degassing on an extrusion process, with respect to extrudate quality and drug release properties. Processed formulations were extruded with and without a degassing vent port at various locations along the barrel. All the experiments were performed un...

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Detalhes bibliográficos
Publicado no:Eur J Pharm Sci
Main Authors: Alshahrani, Saad M., Morott, Joseph T., Alshetaili, Abdullah S., Tiwari, Roshan V., Majumdar, Soumyajit, Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667714/
https://ncbi.nlm.nih.gov/pubmed/26296861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2015.08.008
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