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Influence of Degassing on Hot-Melt Extrusion Process

The present study aimed to evaluate the effect of degassing on an extrusion process, with respect to extrudate quality and drug release properties. Processed formulations were extruded with and without a degassing vent port at various locations along the barrel. All the experiments were performed un...

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Dettagli Bibliografici
Pubblicato in:Eur J Pharm Sci
Autori principali: Alshahrani, Saad M., Morott, Joseph T., Alshetaili, Abdullah S., Tiwari, Roshan V., Majumdar, Soumyajit, Repka, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667714/
https://ncbi.nlm.nih.gov/pubmed/26296861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2015.08.008
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