The Effects of Polymer Carrier, Hot Melt Extrusion Process and Downstream Processing Parameters on the Moisture Sorption Properties of Amorphous Solid Dispersions

OBJECTIVE: The aim of this study was to evaluate the effect of polymer carrier, hot melt extrusion (HME) and downstream processing parameters on the water uptake properties of amorphous solid dispersions. METHODS: Three polymers and a model drug were used to prepare amorphous solid dispersions utili...

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Bibliographic Details
Published in:J Pharm Pharmacol
Main Authors: Feng, Xin, Vo, Anh, Patil, Hemlata, Tiwari, Roshan V., Alshetaili, Abdullah S., Pimparade, Manjeet B., Repka, Michael A.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612492/
https://ncbi.nlm.nih.gov/pubmed/26589107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jphp.12488
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