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Dual-Mechanism Gastroretentive Drug Delivery System Loaded with an Amorphous Solid Dispersion Prepared by Hot-Melt Extrusion
In the present study, we aimed to prepare a gastroretentive drug delivery system that would be both highly resistant to gastric emptying via multiple mechanisms and would also potentially induce in situ supersaturation. The bioadhesive floating pellets, loaded with an amorphous solid dispersion, wer...
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| Publicado no: | Eur J Pharm Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5477177/ https://ncbi.nlm.nih.gov/pubmed/28257881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2017.02.040 |
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