Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

Faithful DNA replication with correct termination is essential for genome stability and transmission of genetic information. Here we have investigated the potential roles of Topoisomerase II (Top2) and the RecQ helicase Sgs1 during late stages of replication. We find that cells lacking Top2 and Sgs1...

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Publicado en:PLoS Genet
Autores principales: Mundbjerg, Kamilla, Jørgensen, Signe W., Fredsøe, Jacob, Nielsen, Ida, Pedersen, Jakob Madsen, Bentsen, Iben Bach, Lisby, Michael, Bjergbaek, Lotte, Andersen, Anni H
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668019/
https://ncbi.nlm.nih.gov/pubmed/26630413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005697
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