Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

Faithful DNA replication with correct termination is essential for genome stability and transmission of genetic information. Here we have investigated the potential roles of Topoisomerase II (Top2) and the RecQ helicase Sgs1 during late stages of replication. We find that cells lacking Top2 and Sgs1...

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Vydáno v:PLoS Genet
Hlavní autoři: Mundbjerg, Kamilla, Jørgensen, Signe W., Fredsøe, Jacob, Nielsen, Ida, Pedersen, Jakob Madsen, Bentsen, Iben Bach, Lisby, Michael, Bjergbaek, Lotte, Andersen, Anni H
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668019/
https://ncbi.nlm.nih.gov/pubmed/26630413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005697
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