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DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation

To investigate the importance of topoisomerases for transcription of the galactose induced genes, we have studied the expression of GAL1, GAL2, GAL7 and GAL10 in Saccharomyces cerevisiae cells deficient for topoisomerases I and II. We find that topoisomerases are required for transcriptional activat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Roedgaard, Morten, Fredsoe, Jacob, Pedersen, Jakob Madsen, Bjergbaek, Lotte, Andersen, Anni Hangaard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501763/
https://ncbi.nlm.nih.gov/pubmed/26173127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132739
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