Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

Faithful DNA replication with correct termination is essential for genome stability and transmission of genetic information. Here we have investigated the potential roles of Topoisomerase II (Top2) and the RecQ helicase Sgs1 during late stages of replication. We find that cells lacking Top2 and Sgs1...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Mundbjerg, Kamilla, Jørgensen, Signe W., Fredsøe, Jacob, Nielsen, Ida, Pedersen, Jakob Madsen, Bentsen, Iben Bach, Lisby, Michael, Bjergbaek, Lotte, Andersen, Anni H
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668019/
https://ncbi.nlm.nih.gov/pubmed/26630413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005697
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