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Identification of DNA lesions using a third base pair for amplification and nanopore sequencing
Damage to the genome is implicated in the progression of cancer and stress-induced diseases. DNA lesions exist in low levels, and cannot be amplified by standard PCR because they are frequently strong blocks to polymerases. Here, we describe a method for PCR amplification of lesion-containing DNA in...
Gorde:
| Argitaratua izan da: | Nat Commun |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Pub. Group
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4667634/ https://ncbi.nlm.nih.gov/pubmed/26542210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9807 |
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