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Structural Destabilization of DNA Duplexes Containing Single Base Lesions Investigated by Nanopore Measurements
The influence of DNA duplex structural destabilization introduced by a single base-pair modification was investigated by nanopore measurements. A series of eleven modified base pairs were introduced into the context of an otherwise complementary DNA duplex formed by a 17-mer oligomer and a 65-mer ol...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867232/ https://ncbi.nlm.nih.gov/pubmed/24128275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4009825 |
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