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Structural Destabilization of DNA Duplexes Containing Single Base Lesions Investigated by Nanopore Measurements

The influence of DNA duplex structural destabilization introduced by a single base-pair modification was investigated by nanopore measurements. A series of eleven modified base pairs were introduced into the context of an otherwise complementary DNA duplex formed by a 17-mer oligomer and a 65-mer ol...

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Détails bibliographiques
Auteurs principaux: Jin, Qian, Fleming, Aaron M., Ding, Yun, Burrows, Cynthia J., White, Henry S.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867232/
https://ncbi.nlm.nih.gov/pubmed/24128275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4009825
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