Načítá se...

Identification of DNA lesions using a third base pair for amplification and nanopore sequencing

Damage to the genome is implicated in the progression of cancer and stress-induced diseases. DNA lesions exist in low levels, and cannot be amplified by standard PCR because they are frequently strong blocks to polymerases. Here, we describe a method for PCR amplification of lesion-containing DNA in...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Riedl, Jan, Ding, Yun, Fleming, Aaron M., Burrows, Cynthia J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667634/
https://ncbi.nlm.nih.gov/pubmed/26542210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9807
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!