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Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria

Fatty acid degradation protein D32 (FadD32), an enzyme required for mycolic acid biosynthesis and essential for mycobacterial growth, has recently been identified as a valid and promising target for anti-tuberculosis drug development. Here we report the crystal structures of Mycobacterium smegmatis...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Li, Wenjuan, Gu, Shoujin, Fleming, Joy, Bi, Lijun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667280/
https://ncbi.nlm.nih.gov/pubmed/26628098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15493
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