Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis

Mycolic acids are essential components of the mycobacterial cell envelope, and their biosynthetic pathway is a well known source of antituberculous drug targets. Among the promising new targets in the pathway, FadD32 is an essential enzyme required for the activation of the long meromycolic chain of...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Le, Nguyen-Hung, Molle, Virginie, Eynard, Nathalie, Miras, Mathieu, Stella, Alexandre, Bardou, Fabienne, Galandrin, Ségolène, Guillet, Valérie, André-Leroux, Gwenaëlle, Bellinzoni, Marco, Alzari, Pedro, Mourey, Lionel, Burlet-Schiltz, Odile, Daffé, Mamadou, Marrakchi, Hedia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077212/
https://ncbi.nlm.nih.gov/pubmed/27590338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748053
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