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Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria

Fatty acid degradation protein D32 (FadD32), an enzyme required for mycolic acid biosynthesis and essential for mycobacterial growth, has recently been identified as a valid and promising target for anti-tuberculosis drug development. Here we report the crystal structures of Mycobacterium smegmatis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Wenjuan, Gu, Shoujin, Fleming, Joy, Bi, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667280/
https://ncbi.nlm.nih.gov/pubmed/26628098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15493
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