The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids in Mycobacterium tuberculosis

The last steps of the biosynthesis of mycolic acids, essential and specific lipids of Mycobacterium tuberculosis and related bacteria, are catalyzed by proteins encoded by the fadD32-pks13-accD4 cluster. Here, we produced and purified an active form of the Pks13 polyketide synthase, with a phosphopa...

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Detalhes bibliográficos
Main Authors: Gavalda, Sabine, Léger, Mathieu, van der Rest, Benoît, Stella, Alexandre, Bardou, Fabienne, Montrozier, Henri, Chalut, Christian, Burlet-Schiltz, Odile, Marrakchi, Hedia, Daffé, Mamadou, Quémard, Annaïk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740550/
https://ncbi.nlm.nih.gov/pubmed/19436070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006940
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