S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor of Mycobacterium tuberculosis Mycolic Acid Methyltransferases

S-Adenosylmethionine-dependent methyltransferases (AdoMet-MTs) constitute a large family of enzymes specifically transferring a methyl group to a range of biologically active molecules. Mycobacterium tuberculosis produces a set of paralogous AdoMet-MTs responsible for introducing key chemical modifi...

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Detalhes bibliográficos
Main Authors: Vaubourgeix, Julien, Bardou, Fabienne, Boissier, Fanny, Julien, Sylviane, Constant, Patricia, Ploux, Olivier, Daffé, Mamadou, Quémard, Annaïk, Mourey, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Enzyme Catalysis and Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740557/
https://ncbi.nlm.nih.gov/pubmed/19439410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809599200
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