Loading...

N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy

S-glutathionylation of cardiac myosin-binding protein C (cMyBP-C) induces Ca(2+) sensitization and a slowing of cross-bridge kinetics as a result of increased oxidative signaling. Although there is evidence for a role of oxidative stress in disorders associated with hypertrophic cardiomyopathy (HCM)...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Wilder, Tanganyika, Ryba, David M., Wieczorek, David F., Wolska, Beata M., Solaro, R. John
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666985/
https://ncbi.nlm.nih.gov/pubmed/26432840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00339.2015
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!