An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase.

Electrostatic calculations based on the recently solved crystal structure of acetylcholinesterase (acetylcholine acetylhydrolase, EC 3.1.1.7) indicate that this enzyme has a strong electrostatic dipole. The dipole is aligned with the gorge leading to its active site, so that a positively charged sub...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ripoll, D R, Faerman, C H, Axelsen, P H, Silman, I, Sussman, J L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC46668/
https://ncbi.nlm.nih.gov/pubmed/8506359
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky