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MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus
Infection with the murine coronavirus mouse hepatitis virus (MHV) activates the pattern recognition receptors melanoma differentiation-associated gene 5 (MDA5) and Toll-like receptor 7 (TLR7) to induce transcription of type I interferon. Type I interferon is crucial for control of viral replication...
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| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665247/ https://ncbi.nlm.nih.gov/pubmed/26423942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01470-15 |
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