Murine Coronavirus Delays Expression of a Subset of Interferon-Stimulated Genes

The importance of the type I interferon (IFN-I) system in limiting coronavirus replication and dissemination has been unequivocally demonstrated by rapid lethality following infection of mice lacking the alpha/beta IFN (IFN-α/β) receptor with mouse hepatitis virus (MHV), a murine coronavirus. Intere...

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Bibliographic Details
Main Authors: Rose, Kristine M., Elliott, Ruth, Martínez-Sobrido, Luis, García-Sastre, Adolfo, Weiss, Susan R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876584/
https://ncbi.nlm.nih.gov/pubmed/20357099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00211-10
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