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Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus

Previous studies have demonstrated that mouse hepatitis virus (MHV) hepatotropism is determined largely by postentry events rather than by availability of the viral receptor. In addition, mutation of MHV nonstructural protein 2 (ns2) abrogates the ability of the virus to replicate in the liver and i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Ling, Rose, Kristine M., Elliott, Ruth, Van Rooijen, Nico, Weiss, Susan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196400/
https://ncbi.nlm.nih.gov/pubmed/21752905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05075-11
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