Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus

Previous studies have demonstrated that mouse hepatitis virus (MHV) hepatotropism is determined largely by postentry events rather than by availability of the viral receptor. In addition, mutation of MHV nonstructural protein 2 (ns2) abrogates the ability of the virus to replicate in the liver and i...

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Bibliographic Details
Main Authors: Zhao, Ling, Rose, Kristine M., Elliott, Ruth, Van Rooijen, Nico, Weiss, Susan R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196400/
https://ncbi.nlm.nih.gov/pubmed/21752905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05075-11
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