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Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus
Previous studies have demonstrated that mouse hepatitis virus (MHV) hepatotropism is determined largely by postentry events rather than by availability of the viral receptor. In addition, mutation of MHV nonstructural protein 2 (ns2) abrogates the ability of the virus to replicate in the liver and i...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3196400/ https://ncbi.nlm.nih.gov/pubmed/21752905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05075-11 |
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