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Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus

Previous studies have demonstrated that mouse hepatitis virus (MHV) hepatotropism is determined largely by postentry events rather than by availability of the viral receptor. In addition, mutation of MHV nonstructural protein 2 (ns2) abrogates the ability of the virus to replicate in the liver and i...

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Autori principali: Zhao, Ling, Rose, Kristine M., Elliott, Ruth, Van Rooijen, Nico, Weiss, Susan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196400/
https://ncbi.nlm.nih.gov/pubmed/21752905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05075-11
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