Inhibition of Beta Interferon Induction by Severe Acute Respiratory Syndrome Coronavirus Suggests a Two-Step Model for Activation of Interferon Regulatory Factor 3

Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus termed SARS-CoV. We and others have previously shown that the replication of SARS-CoV can be suppressed by exogenously added interferon (IFN), a cytokine which is normally synthesized by cells as a reaction to virus infection....

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Autori principali: Spiegel, Martin, Pichlmair, Andreas, Martínez-Sobrido, Luis, Cros, Jerome, García-Sastre, Adolfo, Haller, Otto, Weber, Friedemann
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC546554/
https://ncbi.nlm.nih.gov/pubmed/15681410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2079-2086.2005
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