Loading...
Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα
Protein Kinase A (PKA) is the major receptor for the cyclic adenosine monophosphate (cAMP) secondary messenger in eukaryotes. cAMP binds to two tandem cAMP-binding domains (CBD-A and -B) within the regulatory subunit of PKA (R), unleashing the activity of the catalytic subunit (C). While CBD-A in RI...
Na minha lista:
| Udgivet i: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4664472/ https://ncbi.nlm.nih.gov/pubmed/26618408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002305 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|