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Extracellular rigidity sensing by talin isoform–specific mechanical linkages
The ability of cells to adhere and sense differences in tissue stiffness is crucial for organ development and function. The central mechanisms by which adherent cells detect extracellular matrix compliance, however, are still unknown. Using two single-molecule–calibrated biosensors that allow the an...
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| Опубликовано в: : | Nat Cell Biol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662888/ https://ncbi.nlm.nih.gov/pubmed/26523364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3268 |
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