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Extracellular rigidity sensing by talin isoform–specific mechanical linkages

The ability of cells to adhere and sense differences in tissue stiffness is crucial for organ development and function. The central mechanisms by which adherent cells detect extracellular matrix compliance, however, are still unknown. Using two single-molecule–calibrated biosensors that allow the an...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Austen, Katharina, Ringer, Pia, Mehlich, Alexander, Chrostek-Grashoff, Anna, Kluger, Carleen, Klingner, Christoph, Sabass, Benedikt, Zent, Roy, Rief, Matthias, Grashoff, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662888/
https://ncbi.nlm.nih.gov/pubmed/26523364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3268
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