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Actin flow and talin dynamics govern rigidity sensing in actin–integrin linkage through talin extension

At cell–substrate adhesion sites, the linkage between actin filaments and integrin is regulated by mechanical stiffness of the substrate. Of potential molecular regulators, the linker proteins talin and vinculin are of particular interest because mechanical extension of talin induces vinculin bindin...

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Podrobná bibliografie
Vydáno v:J R Soc Interface
Hlavní autoři: Hirata, Hiroaki, Chiam, Keng-Hwee, Lim, Chwee Teck, Sokabe, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233758/
https://ncbi.nlm.nih.gov/pubmed/25142525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0734
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