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Actin flow and talin dynamics govern rigidity sensing in actin–integrin linkage through talin extension

At cell–substrate adhesion sites, the linkage between actin filaments and integrin is regulated by mechanical stiffness of the substrate. Of potential molecular regulators, the linker proteins talin and vinculin are of particular interest because mechanical extension of talin induces vinculin bindin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J R Soc Interface
Egile Nagusiak: Hirata, Hiroaki, Chiam, Keng-Hwee, Lim, Chwee Teck, Sokabe, Masahiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233758/
https://ncbi.nlm.nih.gov/pubmed/25142525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0734
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