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Actin flow and talin dynamics govern rigidity sensing in actin–integrin linkage through talin extension
At cell–substrate adhesion sites, the linkage between actin filaments and integrin is regulated by mechanical stiffness of the substrate. Of potential molecular regulators, the linker proteins talin and vinculin are of particular interest because mechanical extension of talin induces vinculin bindin...
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| Pubblicato in: | J R Soc Interface |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233758/ https://ncbi.nlm.nih.gov/pubmed/25142525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2014.0734 |
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