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Extracellular rigidity sensing by talin isoform–specific mechanical linkages

The ability of cells to adhere and sense differences in tissue stiffness is crucial for organ development and function. The central mechanisms by which adherent cells detect extracellular matrix compliance, however, are still unknown. Using two single-molecule–calibrated biosensors that allow the an...

詳細記述

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書誌詳細
出版年:Nat Cell Biol
主要な著者: Austen, Katharina, Ringer, Pia, Mehlich, Alexander, Chrostek-Grashoff, Anna, Kluger, Carleen, Klingner, Christoph, Sabass, Benedikt, Zent, Roy, Rief, Matthias, Grashoff, Carsten
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662888/
https://ncbi.nlm.nih.gov/pubmed/26523364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3268
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