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Cellular effects of LRRK2 mutations
Mutations in leucine-rich repeat kinase 2 (LRRK2) are a relatively common cause of inherited Parkinson's disease (PD) but the mechanism(s) by which mutations lead to disease are poorly understood. Here, I will discuss what is known about LRRK2 in cellular models, focusing on specifically on ass...
Enregistré dans:
| Publié dans: | Biochem Soc Trans |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662252/ https://ncbi.nlm.nih.gov/pubmed/22988867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20120165 |
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