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LRRK2 Pathways Leading to Neurodegeneration

Mutations in LRRK2 are associated with inherited Parkinson’s disease (PD) in a large number of families, and the genetic locus containing the LRRK2 gene contains a risk factor for sporadic PD. The LRRK2 protein contains several domains that suggest a role in cellular signaling, including a kinase do...

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Detalhes bibliográficos
Publicado no:Curr Neurol Neurosci Rep
Autor principal: Cookson, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839465/
https://ncbi.nlm.nih.gov/pubmed/26008812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11910-015-0564-y
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