Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling

Notch signaling plays a crucial role in adult brain function such as synaptic plasticity, memory and olfaction. Several reports suggest an involvement of this pathway in neurodegenerative dementia. Yet, to date, the mechanism underlying Notch activity in mature neurons remains unresolved. In this wo...

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Publicado en:Front Cell Neurosci
Autores principales: Brai, Emanuele, Marathe, Swananda, Astori, Simone, Fredj, Naila Ben, Perry, Elisabeth, Lamy, Christophe, Scotti, Alessandra, Alberi, Lavinia
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659909/
https://ncbi.nlm.nih.gov/pubmed/26635527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00447
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