Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling

Notch signaling plays a crucial role in adult brain function such as synaptic plasticity, memory and olfaction. Several reports suggest an involvement of this pathway in neurodegenerative dementia. Yet, to date, the mechanism underlying Notch activity in mature neurons remains unresolved. In this wo...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Brai, Emanuele, Marathe, Swananda, Astori, Simone, Fredj, Naila Ben, Perry, Elisabeth, Lamy, Christophe, Scotti, Alessandra, Alberi, Lavinia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659909/
https://ncbi.nlm.nih.gov/pubmed/26635527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00447
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