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Notch1 hallmarks fibrillary depositions in sporadic Alzheimer’s disease

BACKGROUND: Notch1 signaling is a cellular cascade with a fundamental role from brain development to adult brain function. Reduction in Notch1 affects synaptic plasticity, memory and olfaction. On the other hand, Notch1 overactivation after brain injury is detrimental for neuronal survival. Some fam...

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Bibliografski detalji
Izdano u:Acta Neuropathol Commun
Glavni autori: Brai, Emanuele, Alina Raio, Noemi, Alberi, Lavinia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929714/
https://ncbi.nlm.nih.gov/pubmed/27364742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0327-2
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