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Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer’s disease

Alzheimer’s disease (AD) is characterized by amyloid β (Aβ) accumulation in the brain and is classified as familial early-onset (FAD) or sporadic late-onset (SAD). Evidences suggest that deficits in the brain expression of insulin degrading enzyme (IDE) and neprilysin (NEP), both proteases involved...

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書誌詳細
主要な著者: Dorfman, Verónica Berta, Pasquini, Laura, Riudavets, Miguel, López-Costa, Juan José, Villegas, Andrés, Troncoso, Juan Carlos, Lopera, Francisco, Castaño, Eduardo Miguel, Morelli, Laura
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266723/
https://ncbi.nlm.nih.gov/pubmed/19019493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2008.09.016
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