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Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry
Neurological disorders such as Alzheimer's disease, stroke and epilepsy are currently marred by the lack of effective treatments to prevent neuronal death. Erroneous cell cycle reentry (CCR) is hypothesized to have a causative role in neurodegeneration. We show that forcing S-phase reentry in c...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648324/ https://ncbi.nlm.nih.gov/pubmed/25822340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.23 |
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