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Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry

Neurological disorders such as Alzheimer's disease, stroke and epilepsy are currently marred by the lack of effective treatments to prevent neuronal death. Erroneous cell cycle reentry (CCR) is hypothesized to have a causative role in neurodegeneration. We show that forcing S-phase reentry in c...

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Publicat a:Cell Death Differ
Autors principals: Marathe, S, Liu, S, Brai, E, Kaczarowski, M, Alberi, L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648324/
https://ncbi.nlm.nih.gov/pubmed/25822340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.23
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