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Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry
Neurological disorders such as Alzheimer's disease, stroke and epilepsy are currently marred by the lack of effective treatments to prevent neuronal death. Erroneous cell cycle reentry (CCR) is hypothesized to have a causative role in neurodegeneration. We show that forcing S-phase reentry in c...
Gespeichert in:
| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4648324/ https://ncbi.nlm.nih.gov/pubmed/25822340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.23 |
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