Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling

Notch signaling plays a crucial role in adult brain function such as synaptic plasticity, memory and olfaction. Several reports suggest an involvement of this pathway in neurodegenerative dementia. Yet, to date, the mechanism underlying Notch activity in mature neurons remains unresolved. In this wo...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Brai, Emanuele, Marathe, Swananda, Astori, Simone, Fredj, Naila Ben, Perry, Elisabeth, Lamy, Christophe, Scotti, Alessandra, Alberi, Lavinia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659909/
https://ncbi.nlm.nih.gov/pubmed/26635527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00447
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