Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling

Notch signaling plays a crucial role in adult brain function such as synaptic plasticity, memory and olfaction. Several reports suggest an involvement of this pathway in neurodegenerative dementia. Yet, to date, the mechanism underlying Notch activity in mature neurons remains unresolved. In this wo...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Brai, Emanuele, Marathe, Swananda, Astori, Simone, Fredj, Naila Ben, Perry, Elisabeth, Lamy, Christophe, Scotti, Alessandra, Alberi, Lavinia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659909/
https://ncbi.nlm.nih.gov/pubmed/26635527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00447
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